Spinal Dysraphism (Myelodysplasia)
Myelodysplasias are congenital spinal cord developmental abnormalities. Specifically, spinal dysraphism occurs due to an incomplete formation of the dorsal median septum, ventral median fissure, hydromyelia or absent central canal or failure of ventral gray column cell body migration.
Age of Onset: Congenital (Signs are first observed when the dogs begin to walk)
Sex Predisposition: Any sex of animal can be affected
Clinical Course:
Clinical signs do not worsen over time
Clinical signs do not worsen over time
Clinical Signs:
Movement
Bunny hopping (simultaneous) gait in pelvic limbs
Paraparesis
Pelvic limb ataxia
Proprioception
Proprioceptive deficits of pelvic limbs
Spinal Reflexes
Normal to exaggerated patellar reflexes
Movement
Bunny hopping (simultaneous) gait in pelvic limbs
Paraparesis
Pelvic limb ataxia
Proprioception
Proprioceptive deficits of pelvic limbs
Spinal Reflexes
Normal to exaggerated patellar reflexes
Spinal - thoracolumbar
Autosomal codominant mutation in the NKX2-8 gene in Weimaraners
For breed-specific genetic testing, click the link(s) below:
https://vgl.ucdavis.edu/test/sd-weimaraner
https://www.eurovetgene.com/spinal-dysraphism
For breed-specific genetic testing, click the link(s) below:
https://vgl.ucdavis.edu/test/sd-weimaraner
https://www.eurovetgene.com/spinal-dysraphism
To read more about this disease click below:
