(Idiopathic) Eosinophilic (Granulomatous) Meningoencephalitis
Eosinophilic meningoencephalitis is characterized by an idiopathic infiltration of eosinophils into central nervous system structures resulting in damage and inflammation.
Age of Onset: 4 months - 5.5 years of age
Sex Predisposition: Males are more likely to be affected
Clinical Course:
Clinical signs may worsen over time
Clinical signs may worsen over time
Clinical Signs:
Behavioral/Mental Awareness
Behavioral abnormalities
Disorientation
Depression
Seizures
Posture and Appearance
All 4 limbs in rigid extension
Head turn, head tilt, or torticollis
Generalized muscle tremors
Movement
Circling
Head pressing
Mild ataxia
Pacing
Paresis
Proprioception
Proprioceptive deficits
Cranial Nerves
Varying cranial nerve abnormalities
Spinal Reflexes
Can be normal or increased/decreased depending on the location of the lesion and the degree of spinal cord involvement
Painful Reactions
May have pain on palpation of the vertebral column over the affected area
Other
Decreased appetite
Excessive salivation
Hypersensitivity to touch and sound
Behavioral/Mental Awareness
Behavioral abnormalities
Disorientation
Depression
Seizures
Posture and Appearance
All 4 limbs in rigid extension
Head turn, head tilt, or torticollis
Generalized muscle tremors
Movement
Circling
Head pressing
Mild ataxia
Pacing
Paresis
Proprioception
Proprioceptive deficits
Cranial Nerves
Varying cranial nerve abnormalities
Spinal Reflexes
Can be normal or increased/decreased depending on the location of the lesion and the degree of spinal cord involvement
Painful Reactions
May have pain on palpation of the vertebral column over the affected area
Other
Decreased appetite
Excessive salivation
Hypersensitivity to touch and sound
Multifocal intracranial (cerebrum and brainstem)
Unknown
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