Hereditary Polyneuropathy/Neuropathy
Hereditary polyneuropathy/neuropathy is an idiopathic degeneration of nerves often characterized by axonal degeneration and hypomyelination.
Age of Onset: 3-18 months of age
Sex Predisposition: Any sex of animal can be affected
Clinical Course:
Clinical signs worsen slowly over time
Clinical signs worsen slowly over time
Clinical Signs:
Movement
Collapse
Hyporeflexia
Progressive paraparesis to tetraparesis
Exercise intolerance
Proprioception
Proprioceptive deficits
Spinal Reflexes
Decreased spinal reflexes
Special Functions (e.g. respiration; urination)
Inspiratory stridor
Megaesophagus
Muscle Atrophy
General muscle atrophy
Muscles of mastication (CN V)
Other
Abnormal vocalization
Hyperesthesia
Movement
Collapse
Hyporeflexia
Progressive paraparesis to tetraparesis
Exercise intolerance
Proprioception
Proprioceptive deficits
Spinal Reflexes
Decreased spinal reflexes
Special Functions (e.g. respiration; urination)
Inspiratory stridor
Megaesophagus
Muscle Atrophy
General muscle atrophy
Muscles of mastication (CN V)
Other
Abnormal vocalization
Hyperesthesia
Spinal cord
Unknown
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