Meningoencephalitis of Unknown Origin (MUO)
Meningoencephalitis of unknown origin is characterized by immune-mediated inflammation of the central nervous system with no identifiable cause.
Age of Onset: Any age of animal can be affected although young dogs are more commonly affected
Sex Predisposition: Any sex of animal can be affected
Clinical Course:
Clinical signs may worsen over time
Clinical signs may worsen over time
Clinical Signs:
Behavioral/Mental Awareness
Abnormal vocalization
Aggression
Dull mentation
Excitation
Restlessness
Seizures
Sleepiness
Posture and Appearance
Head tilt
Dererebrate rigdity
Movement
Ataxia
Circling
Paresis
Tremors
Falling over
Proprioception
Proprioceptive deficits
Spinal Reflexes
Reduced spinal reflexes (withdrawal and/or patellar)
Cranial Nerves
Blindness
Variable cranial nerve deficits
Nystagmus
Reduce menace response
Painful Reactions
Pain on palpation of the cervical spine
Behavioral/Mental Awareness
Abnormal vocalization
Aggression
Dull mentation
Excitation
Restlessness
Seizures
Sleepiness
Posture and Appearance
Head tilt
Dererebrate rigdity
Movement
Ataxia
Circling
Paresis
Tremors
Falling over
Proprioception
Proprioceptive deficits
Spinal Reflexes
Reduced spinal reflexes (withdrawal and/or patellar)
Cranial Nerves
Blindness
Variable cranial nerve deficits
Nystagmus
Reduce menace response
Painful Reactions
Pain on palpation of the cervical spine
Intracranial- multifocal
Unknown
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