Spongiform Leukoencephalomyelopathy
Spongiform leukoencephalopathy is a generalized progressive degenerative vacuolation of white matter of the brain and spinal cord.
Age of Onset: 2-9 weeks of age
Sex Predisposition: Any sex of animal can be affected
Clinical Course:
Clinical signs worsen over time
Clinical signs worsen over time
Clinical Signs:
Behavioral/Mental Awareness
Seizures
Movement
Generalized whole body tremors
Ataxia
Paresis to paralysis
Limb spasticity
Proprioception
Postural reaction deficits
Cranial Nerves
Cranial nerve dysfunction (dropped jaw, hypoglossal dysfunction, nystagmus)
Vision and audition remained intact
Absent menace response
Special Functions (e.g. respiration; urination)
Dysphagia
Excessive salivation
Behavioral/Mental Awareness
Seizures
Movement
Generalized whole body tremors
Ataxia
Paresis to paralysis
Limb spasticity
Proprioception
Postural reaction deficits
Cranial Nerves
Cranial nerve dysfunction (dropped jaw, hypoglossal dysfunction, nystagmus)
Vision and audition remained intact
Absent menace response
Special Functions (e.g. respiration; urination)
Dysphagia
Excessive salivation
White matter of the brain and spinal cord
Unknown
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