(Idiopathic) Eosinophilic (Granulomatous) Meningoencephalitis
Idiopathic infiltration of eosinophils into central nervous system structures resulting in damage and inflammation.
Age of Onset: 4 months - 5.5 years of age
Sex Predisposition: Males are more likely to be affected
Clinical Course:
Clinical signs may worsen over time
Clinical signs may worsen over time
Clinical Signs:
Behavioral/Mental Awareness
Behavioral abnormalities
Depression
Seizures
Somnolence
Posture and Appearance
All 4 limbs in rigid extension
Deviation of the head to the right
Generalized muscle tremors
Torticollis to the right
Movement
Circling
Collapse
Head pressing
Mild ataxia
Pacing
Tetraparesis
Proprioception
Absent in front limbs
Delayed in hind limbs
Cranial Nerves
Anisocoria
Dilated non-responsive left pupil
Mildly contracted facial muscles
Spinal Reflexes
Decreased both front limbs
Special Reflexes (e.g. cutaneous trunci)
Decreased gag reflex
Painful Reactions
Manipulation of the front limbs
Palpation of cervical spine
Palpation of thoracic spine
Other
Decreased appetite
Excessive salivation
Hypersensitivity to touch and sound
Behavioral/Mental Awareness
Behavioral abnormalities
Depression
Seizures
Somnolence
Posture and Appearance
All 4 limbs in rigid extension
Deviation of the head to the right
Generalized muscle tremors
Torticollis to the right
Movement
Circling
Collapse
Head pressing
Mild ataxia
Pacing
Tetraparesis
Proprioception
Absent in front limbs
Delayed in hind limbs
Cranial Nerves
Anisocoria
Dilated non-responsive left pupil
Mildly contracted facial muscles
Spinal Reflexes
Decreased both front limbs
Special Reflexes (e.g. cutaneous trunci)
Decreased gag reflex
Painful Reactions
Manipulation of the front limbs
Palpation of cervical spine
Palpation of thoracic spine
Other
Decreased appetite
Excessive salivation
Hypersensitivity to touch and sound
Brain and spinal cord
Unknown
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