Polyneuropathy (Distal Symmetrical Polyneuropathy)
Distal symmetrical polyneuropathies are chronic progression neurologic diseases resulting from dysfunction of peripheral motor neurons.
Age of Onset: 8-10 years of age
Sex Predisposition: Any sex of animal can be affected
Clinical Course:
Clinical signs worsen over time, progressing from paraparesis to tetraparesis.
Clinical signs worsen over time, progressing from paraparesis to tetraparesis.
Clinical Signs:
Posture and Appearance
Dropped hock stance
Movement
Paraparesis to tetraparesis
Pseudohypermetric gait in the pelvic limbs
Proprioception
Proprioceptive deficits in affected limbs
Spinal Reflexes
Hyporeflexia
Muscle Atrophy
Bilateral masticatory muscle atrophy
Atrophy of distal appendicular muscles
Posture and Appearance
Dropped hock stance
Movement
Paraparesis to tetraparesis
Pseudohypermetric gait in the pelvic limbs
Proprioception
Proprioceptive deficits in affected limbs
Spinal Reflexes
Hyporeflexia
Muscle Atrophy
Bilateral masticatory muscle atrophy
Atrophy of distal appendicular muscles
Peripheral nerves
Suspected autosomal recessive inheritance
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