Hereditary Quadriplegia and Amblyopia
This disease is caused by an autosomal recessive mutation leading to cerebellar degeneration causing associated clinical signs.
Age of Onset: Greater than 10 days of age
Sex Predisposition: Any sex of animal can be affected
Clinical Course:
Clinical signs may progress with age
Clinical signs may progress with age
Clinical Signs:
Behavioral/Mental Awareness
Seizures
Movement
Ataxia
Tetraplegia
Muscle spasms
“Swimming” motion of the limbs
Tremor
Cranial Nerves
Nystagmus
Amblyopia (lazy eye)
Behavioral/Mental Awareness
Seizures
Movement
Ataxia
Tetraplegia
Muscle spasms
“Swimming” motion of the limbs
Tremor
Cranial Nerves
Nystagmus
Amblyopia (lazy eye)
Intracranial
Autosomal recessive inheritance
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