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Sensory Neuropathy
  • Description
  • Signalment
  • Clinical Features
  • Neurolocalization
  • Genetics
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​Peripheral neuropathies can involve either the sensory or motor systems, or both. Sensory neuropathies involve exclusively or predominantly sensory nerve cells with minor involvement of motor neurons. With this disorder, there may also be concomitant autonomic signs.
Age of Onset: Insidious onset between 2 to 8 months of age
Sex Predisposition: Any sex of animal can be affected
Clinical Course:
​Clinical signs worsen over time with pelvic limbs being more severely affected compared to thoracic limbs
Clinical Signs:
Behavioral/Mental Awareness
Self-mutilation to distal limbs

Movement
Ataxia
Dysmetria
"Bunny hopping gait"

Proprioception
Proprioceptive deficits

Cranial Nerves
Reduced palpebral reflex

Spinal Reflexes
Hypo-reflexia

Special Reflexes (e.g. cutaneous trunci)
Reduced to absent cutaneous trunci reflex
Reduced to absent anal reflex (with normal anal tone)

Special Functions (e.g. respiration; urination)
Urinary incontinence (urine dribbling)
Regurgitation

Pain Sensation
Absent superficial skin sensation in all distal limbs, ventral trunk, and head (with the exception of the lips and inside of the nostril)
Peripheral nervous system
Mitochondrial tRNA Tyr gene deletion

For breed specific genetic testing, follow the links below:
https://vgl.ucdavis.edu/test/san-gr​
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