Meningoencephalitis of Unknown Origin (MUO)
Meningoencephalitis of unknown origin is characterized by immune-mediated inflammation of the central nervous system with no identifiable cause.
Age of Onset: Any age of animal can be affected
Sex Predisposition: Any sex of animal can be affected
Clinical Course:
Clinical signs may worsen over time
Clinical signs may worsen over time
Clinical Signs:
Behavioral/Mental Awareness
Abnormal vocalization
Aggression
Decreased mentation
Excitation/Restlessness
Seizures
Lethargy
Posture and Appearance
Head tilt
Movement
Ataxia
Circling
Paresis
Tremors
Weakness
Proprioception
Paw placement deficits
Cranial Nerves
Blindness
Cranial nerve deficits
Nystagmus
Reduce menace response
Spinal Reflexes:
Can be normal or increased/decreased depending on the location of the lesion and the degree of spinal cord involvement
Painful Reactions
Pain on palpation of the cervical vertebral column
May have pain on palpation of the vertebral column over the affected area
Behavioral/Mental Awareness
Abnormal vocalization
Aggression
Decreased mentation
Excitation/Restlessness
Seizures
Lethargy
Posture and Appearance
Head tilt
Movement
Ataxia
Circling
Paresis
Tremors
Weakness
Proprioception
Paw placement deficits
Cranial Nerves
Blindness
Cranial nerve deficits
Nystagmus
Reduce menace response
Spinal Reflexes:
Can be normal or increased/decreased depending on the location of the lesion and the degree of spinal cord involvement
Painful Reactions
Pain on palpation of the cervical vertebral column
May have pain on palpation of the vertebral column over the affected area
Intracranial
Unknown
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