(Idiopathic) Eosinophilic (Granulomatous) Meningoencephalitis
Idiopathic infiltration of eosinophils into central nervous system structures resulting in damage and inflammation.
Age of Onset: 4 months - 5.5 years of age
Sex Predisposition: Males are more likely to be affected
Clinical Course:
Clinical signs may worsen over the course of 1 week to 1 year
Clinical signs may worsen over the course of 1 week to 1 year
Clinical Signs:
Behavioral/Mental Awareness
Behavioral abnormalities
Depression/Somnolence
Seizures
Loss of learned behaviors
Posture and Appearance
Torticollis
Movement
Circling
Collapse
Head pressing
Mild ataxia
Pacing
Tetraparesis
Generalized muscle tremors
Proprioception
Proprioceptive deficits (thoracic limbs > pelvic limbs)
Cranial Nerves
Anisocoria
Reduced to absent menace response
Cortical blindness
Variable cranial nerve deficits
Spinal Reflexes
Can be normal or increased/decreased depending on the location of the lesion and the degree of spinal cord involvement
Painful Reactions
May have pain on palpation of the vertebral column over the affected area
Other
Decreased appetite
Excessive salivation
Hypersensitivity to touch and sound
Behavioral/Mental Awareness
Behavioral abnormalities
Depression/Somnolence
Seizures
Loss of learned behaviors
Posture and Appearance
Torticollis
Movement
Circling
Collapse
Head pressing
Mild ataxia
Pacing
Tetraparesis
Generalized muscle tremors
Proprioception
Proprioceptive deficits (thoracic limbs > pelvic limbs)
Cranial Nerves
Anisocoria
Reduced to absent menace response
Cortical blindness
Variable cranial nerve deficits
Spinal Reflexes
Can be normal or increased/decreased depending on the location of the lesion and the degree of spinal cord involvement
Painful Reactions
May have pain on palpation of the vertebral column over the affected area
Other
Decreased appetite
Excessive salivation
Hypersensitivity to touch and sound
Brain and spinal cord
Unknown
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