Hereditary Polyneuropathy/Neuropathy
Hereditary polyneuropathy/neuropathy is an idiopathic degeneration of nerves often characterized by axonal degeneration and hypomyelination.
Age of Onset: 8-9 years of age
Sex Predisposition: Any sex of animal can be affected
Clinical Course:
Clinical signs worsen over time, primarily affecting the branches of the sciatic nerve
Clinical signs worsen over time, primarily affecting the branches of the sciatic nerve
Clinical Signs:
Movement
Collapse
Hyporeflexia
Progressive paraparesis
Proprioception
Proprioceptive deficits
Spinal Reflexes
Hyporeflexia
Special Functions (e.g. respiration; urination)
Exercise intolerance
Muscle Atrophy
General muscle atrophy
Other
Abnormal vocalization
Hyperesthesia
Movement
Collapse
Hyporeflexia
Progressive paraparesis
Proprioception
Proprioceptive deficits
Spinal Reflexes
Hyporeflexia
Special Functions (e.g. respiration; urination)
Exercise intolerance
Muscle Atrophy
General muscle atrophy
Other
Abnormal vocalization
Hyperesthesia
Peripheral nerve
Autosomal recessive inheritance
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